p62 and NBR1 functions are dispensable for aggrephagy in mouse
Scientists prove the “neuroprotective” function of p62 protein in a p62 app
p62 is a well-characterized autophagy receptor that recognizes and sequesters specific cargoes into auto- phagosomes for degradation p62
p62com p62SQSTM1 to modulate S et al Presynaptic APP levels and synaptic homeostasis are regulated by Akt phosphorylation of huntingtin β-asarone modulates Beclin-1, LC3 and p62 expression to attenuate Aβ40 and Aβ42 levels in APPPS1 transgenic mice with Alzheimer's disease Mol Med Rep In the present study, we analyzed the interaction between p62, an adapter protein, and an APP-related molecule, and found that p62 interacted with the C-
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